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It's likely tied to the fact that when you're stressed, cortisol is secreted. This is our ‘fight or flight’ reaction that evolved in humans to keep us alive when large animals were running after us as cavemen. But today a stressful job makes us feel like a lion is running after us 40 hours a week.
When cortisol is released it produces a quick burst of energy along with a lower sensitivity to pain. In caveman times the release of cortisol was replaced by a relaxation response so that cortisol wasn’t constantly flowing through the body. Too much cortisol for prolonged periods of time creates a slew of side effects like high blood pressure and lowered immunity. Stress can also lead to heart attacks, abdominal fat, strokes, and so much more.
Researchers from The Epidemiology and Public Health Research Center demonstrated why being vigilant about stress is so important. The study, reported on Science Daily, followed 7,268 people, asking them to fill out a questionnaire on their stress levels. The study, published in the European Heart Journal, asked participants a simple question:
To what extent do you consider the stress or pressure that you have experienced in your life has an effect on your health?
Participants could choose from “not at all,” “a little,” “moderately,” “a lot,” or “extremely.” Participants were later asked about stress levels and other things that might impact their health like smoking, alcohol consumption, and physical activity.
Researchers found that those who reported that their health was impacted “a lot” or “extremely” by stress were 2.12 times more likely to have or die as a result of a heart attack. Capacity for dealing with stress had a large impact.
According to Hermann Nabi on Science Daily, "the main message is that complaints from patients concerning the effect of stress on their health should not be ignored in a clinical environment, because they may indicate an increased risk of developing and dying of coronary disease. Future studies of stress should include perceptions of patients concerning the effect of stress on their health."

